Outbreak Update: Since the last brief (6 July 2021), 3,084,363 new confirmed coronavirus disease 2019 (COVID-19) cases, including 55,658 new deaths, have been reported globally. To date, a global total of 186,677,181 COVID-19 cases and 4,035,732 related deaths (case fatality ratio (CFR): 2.2%) have been reported from 225 countries and territories to the World Health Organization (WHO). The distribution of cumulative cases (proportion of global cases) from the WHO reporting regions (excluding Africa) are as follows: Eastern Mediterranean Region 9,894,703 (5%), European Region 57,023,572 (31%), Region of the Americas 73,876,425 (40%), South-East Asia Region 36,038,117 (19%) and Western Pacific Region 3,803,525 (2%). In the last seven days, the five countries reporting the highest number of new cases globally are Brazil (326,978), India (289,147), Indonesia (253,801), the United Kingdom (217,811) and the Russian Federation (173,179). For more detailed information on cases and deaths reported outside of Africa, refer to the WHO COVID-19 dashboard.