Since the last brief (2 February 2021), 3,221,234 new confirmed coronavirus disease 2019 (COVID-19) cases and 89,503 new deaths have been reported globally. To date, a total of 105,825,060 COVID-19 cases and 2,312,719 related deaths (case fatality rate (CFR): 2.2%) have been reported from 225 countries and territories. The distribution of cumulative cases (proportion of global cases) from the World Health Organization (WHO) reporting regions (excluding Africa) are as follows: Eastern Mediterranean Region 4,833,090 (5%), European Region 35,543,066 (31%), Region of the Americas 47,072,257 (45%), South-East Asia Region 13,187,514 (13%) and Western Pacific Region 1,489,368 (1%). Over the last seven days, the United States, Brazil, France, the United Kingdom, and Russia have reported more than 100k new cases. For more detailed information on cases and deaths being reported outside of Africa, refer to the WHO daily situation reports.