Global Update (non-endemic countries): As of 24 August 2022, 45,535 confirmed cases of monkeypox and 110 deaths were reported from 98 countries/territories globally. The countries reporting the majority of cases are mainly in Europe and North America.
Africa update (endemic and non-endemic countries): Since the last brief (17 August 2022), a total of 219 new cases (48 confirmed; 171 suspected) and no new deaths of monkeypox were reported from the Democratic Republic of Congo (DRC) and Nigeria. This is a 54% increase in the number of new confirmed cases since the last brief. Cumulatively, 3,451 cases (459 confirmed; 2,992 suspected) and 105 deaths (case fatality rate [CFR]: 3%) of monkeypox were reported from 11 African Union (AU) Member States (MS) since January 2022 (Table 1).
DRC: Since the last brief (17 August 2022), 114 new suspected cases and no new deaths of monkeypox were reported in DRC. Cumulatively, 2,380 cases (163 confirmed; 2,217 suspected) and 93 deaths (CFR: 3.9%) were reported from 128 health zones in 21 provinces of DRC.Nigeria: Since the last brief (17 August 2022), the Nigeria Center for Disease Control (NCDC) reported 105 new cases (48 confirmed; 57 suspected) and no new deaths of monkeypox in Nigeria. This is a greater than 100% increase in the number of new confirmed cases compared to the last brief. Cumulatively, 750 cases (220 confirmed; 530 suspected) and four deaths (CFR: 0.5%) of monkeypox were reported from 34 states in Nigeria.
 Global case and death numbers are inclusive of numbers being reported in Africa.
 Cameroon, the Central African Republic, the Democratic Republic of the Congo, Gabon, Ghana, Côte d’Ivoire, Liberia, Nigeria, the Republic of the Congo, and Sierra Leone