Outbreak Brief 25: Mpox in Africa Union Member States

4 January 2023

Global Update (non-endemic countries): As of 28 December 2022, 83,582 confirmed cases of mpox and 282 deaths were reported from 110 countries/territories globally. The countries reporting the majority of cases are mainly in Europe and the Americas.
Africa update (endemic and non-endemic countries): Since the beginning of 2022, the continent has reported 1,262 confirmed cases and 226 deaths (CFR: 18%) of mpox from eight endemic Africa Union (AU) Member States (MS): Benin (3 confirmed cases; 0 confirmed deaths), Cameroon (18; 3), Central African Republic (CAR) (13; 3), Congo (5; 3), Democratic Republic of Congo (DRC) (319; 204), Ghana 116; 4), Liberia (4; 0), Nigeria (753; 7) and five non-endemic MS: Egypt (4; 0), Morocco (3; 0), Mozambique (1; 1), South Africa (5; 0) and Sudan (18; 1). This week, 47 new confirmed cases and seven new deaths of mpox were reported from CAR and DRC.
Central African Republic: Since the last update (27 May 2022), the MoH reported 5 new confirmed cases and one new death (CFR: 20%) of mpox. This is a 17% decrease in the number of new confirmed cases and no percentage change in the number of new confirmed deaths compared to the last brief.
Cumulatively, 13 confirmed cases and three deaths (CFR: 23%) of mpox were reported from six
districts.