Outbreak Brief 110: Coronavirus Disease 2019 (COVID-19) Pandemic

Outbreak Update: As of 21 February 2022, a global total of 423,235,750 COVID-19 cases and 5,811,307 related deaths (case fatality ratio (CFR): 1.4%) have been reported by 227 countries and territories to the World Health Organization (WHO). The distribution of cumulative cases (proportion of global cases) from the WHO regions (excluding Africa) are as follows: Eastern Mediterranean Region 17,671,510 (4%), European Region 172,533,219 (40%), Region of the Americas 145,474,447 (35%), South-East Asia Region 54,945,592 (13%) and Western Pacific Region 21,161,427 (5%). In the last seven days, the five countries reporting the highest number of new cases globally are Germany (1,215,867), Russia (1,208,791), Brazil (741,844), the United States (704.431) and Republic of Korea (652,940). For more detailed information on cases and deaths reported outside of Africa, refer to the WHO COVID-19 dashboard.