Statement on Antigen Rapid Tests for Mpox Diagnosis, 30 October 2024

No Antigen Rapid Diagnostic Test (RDT) has demonstrated the minimum requirement for mpox testing. On 13 August 2024, Africa Centres for Disease Control and Prevention (Africa CDC) declared the ongoing mpox outbreak a Public Health Emergency of Continental Security (PHECS). This was followed the next day by the World Health Organization (WHO), which extended the […]

African Vaccine Manufacturing Mapping – Supply and Demand Landscape

This slide deck, presented at the Developing Countries Vaccine Manufacturers Network International Annual General Meeting in October 2024, describes updated results from a study to assess the current and planned state of vaccine manufacturing in Africa and provides insights into what’s needed to develop a robust and sustainable vaccine manufacturing ecosystem. We surveyed African vaccine […]

Mpox Molecular Diagnostic Tests(RT-PCR)

On 13 August 2024, Africa Centres for Disease Control and Prevention (Africa CDC) declared the ongoing mpox outbreak a Public Health Emergency of Continental Security (PHECS). The World Health Organization (WHO) followed this the next day, which extended the alert internationally as a Public Health Emergency of International Concern (PHEIC). After these declarations, many countries […]

Empowering Africa’s healthcare future: the crucial role of human capital development in bio- and pharmaceutical manufacturing

Introduction Africa, a continent of immense potential and diversity, has long grappled with complex healthcare challenges. The COVID-19 pandemic has accentuated the urgency of fortifying the continent’s healthcare infrastructure. The Africa Union has since set a target to manufacture 60% of vaccines used on the continent locally by 2040, and established the Partnership for African […]

HIV drug resistance to integrase inhibitors in low- and middle-income countries

In the landscape of antiretroviral therapies, the transition to tenofovir-lamuvidine-dolutegarvir in several African countries is being implemented regardless of viral load among people living with HIV. However, people with unsuppressed viral load during transition stand at risk of developing HIV resistance to dolutegravir. The present paper therefore, underscores the need to ensure viral load suppression […]

Business and Operational Models for African Biomanufacturing Training Centres

Introduction & Background The African Union (AU) has set an ambitious goal to increase local vaccine production to 60% of the continent’s requirements by 2040. The AU’s Partnerships for African Vaccine Manufacturing (PAVM), hosted by the Africa Centres for Disease Control and Prevention (Africa CDC), was established in 2021 and estimates between 900-1600 current Full […]

Meeting Report: Optimizing Efficiency and Impact in the African Clinical Trials Ecosystem

Executive Summary In May 2023, Africa CDC and AUDA-NEPAD convened sixty experts from across the continent and the globe to discuss concrete solutions for strengthening the impact and efficiency of the African clinical trials ecosystem, with the goal of speeding access to new lifesaving technologies in line with public health priorities. This meeting—rooted in aspirations […]