Mpox Situation in Africa: Guidance for schools and childcare facilities

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Mpox Situation in Africa: Guidance for schools and childcare facilities

Purpose:

This guidance is for school authorities, healthcare workers, and students to help them prepare and respond to the current mpox outbreak. It highlights key actions to prevent infections in schools to continue in-person learning during mpox outbreak and avoid delayed school openings, school closures and learning disruption.

Introduction
On 13 August 2024, Africa Centres for Disease Control and Prevention (Africa CDC) declared the resurgence of mpox cases in Africa as a Public Health Emergency of Continental Security (PHECS). The WHO declared on August 14, 2024, that the escalation of mpox cases in the Democratic Republic of Congo and its expansion to neighbouring countries constitutes a Public Health Emergency of International Concern (PHEIC). The spread poses a public health threat to other Member States and demands a coordinated international response. Children less than 15 years of age have accounted for 70 % of cases to date in Africa during the ongoing 2024 outbreak.

There are uncertainties regarding the transmission dynamics of mpox and its impact on children. Available data suggest that the disease burden among children varies within and between countries, depending on the circulating virus clade. Most reported child deaths from mpox have occurred in the Northern and Western parts of DRC, where clade I is predominant. In contrast, no deaths have been reported in Eastern DRC or in the newly affected countries of Burundi, Rwanda, Kenya, and Uganda, where outbreaks are linked to clade Ib. Where data are available, infants and children under five years of age are at the highest risk of severe disease and death, particularly where prompt, high-quality case management is limited or unavailable.

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This slide deck, presented at the Developing Countries Vaccine Manufacturers Network International Annual General Meeting in October 2024, describes updated results from a study to assess the current and planned state of vaccine manufacturing in Africa and provides insights into what’s needed to develop a robust and sustainable vaccine manufacturing ecosystem.

We surveyed African vaccine manufacturers to better understand their current manufacturing capacity and capabilities, the progress they’ve made since 2023, and their future outlooks. This information can help stakeholders and funders better coordinate and prioritize actions to build a successful African vaccine manufacturing ecosystem.

Corporate author(s): Africa Centres for Disease Control and Prevention (Africa CDC); Clinton Health Access Initiative (CHAI); PATH

Publication date: October 2024

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African Vaccine Manufacturing Mapping | Supply and Demand LandscapeDownload