Outbreak Brief 1: Ebola virus disease (EVD) in Uganda

27 September 2022

Outbreak update: On 20 September 2022, the Uganda Ministry of Health (MoH) reported a confirmed case of Ebola virus disease (EVD) in Mubende district. The case was a 24-year-old male who developed high-grade fever, convulsions, blood-stained vomitus, diarrhoea, loss of appetite and pain while swallowing on 11 September 2022. On 17 September, blood samples were collected and on 19 September, Uganda Virus Research Institute (UVRI) confirmed EVD (Sudan strain) by polymerase chain reaction (PCR). The patient died on 19 September 2022 and was buried following a dignified burial protocol. Further investigations have revealed that the onset of the outbreak dates back to the month of August 2022.
Since the beginning of the outbreak and as of 27 September, 43 cases including 24 confirmed cases, 19 probable cases with 23 deaths (case fatality rate [CFR]: 53.5%) were reported from three health districts: Mubende (37 cases; 22 deaths), Kassanda (3; 1) and Kyegegwa (3; 0) districts. Seventy eight percent (18) of deaths were reported from communities while 22% (5) were reported from health facilities; one of whom was a health care worker. Of the 43 confirmed and probable cases reported, 58% (25) are female, 42% (18) are male and the mean age is 27 years. A total of 37 cases are currently hospitalised however, 13 cases including a confirmed case have escaped from the isolation centre.